Did you know that: “The first cases, reported in the early 1900's, and characterized by a triad of symptoms that included chronic sinusitis, bronchiectasis, and situs inversus became known as Kartagener syndrome. Subsequently, patients with Kartagener syndrome, as well as other patients with chronic sinusitis and bronchiectasis, were noted to have “immotile” cilia and defects in the ultrastructural organization of cilia. Initially, the term “immotile cilia syndrome” was used to describe this disorder; however, later studies showed that most cilia were motile, but exhibited a stiff, uncoordinated and/or ineffective beat. The name was changed to “primary ciliary dyskinesia” to more appropriately describe its heterogeneous genetic base and the ciliary dysfunction, as well as to distinguish it from the secondary ciliary defects acquired following multiple causes of epithelial injury.” ~ Clinical and Genetic Aspects of Primary Ciliary Dyskinesia / Kartagener Syndrome (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739704/)
The more you know…
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