Primary ciliary dyskinesia (PCD) is a congenital motile ciliopathy, associated with chronic sinusitis due to impaired mucociliary clearance. Pifferi et al 6 hypothesise that olfactory function might be impaired in this condition due to primary ciliopathy affecting the olfactory cilia. There certainly seems to be growing evidence of this in other ciliopathies.7 The idea is an interesting one and would certainly be useful to know from a clinical point of view, if only to better counsel patients as to the likelihood of improvement of this very important symptom with treatment.
https://thorax.bmj.com/content/73/10/897
The more you know…
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